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Biopharmaceutics and Relevant Pharmacokinetics

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Biopharmaceutics
1. Introduction to Biopharmaceutics...1
2. Some Fundamental Principles and Concepts...8
3. Ranking of Drugs and Several Formulations of One Drug...12
4. Dosage of Drugs in Infants, Children and Adults...18
5. Drug Absorption and Transfort in the Gastrointestinal Tract I. Mechanism...26
6. Drug absorption and Transport in the Gastrointestinal Tract II. Multicompartment Diffusional Models...32
7. Transport od Drugs Through Membranes and Barries Other Thean the Gastrointestinal Tract...43
8. Relationships Betwen Dosage Forms, Dosage Regimens and Pharmacokinetics...51
9. Relationships Among Form of Drug, Dosage Form, Routes of Administration and Plasma Concentration and Urinary Excretion Curves...58
10. Introduction to Disintegration of Dosage Form in Vitro and in Vivo...64
11. methods of Determining Disintegration Time in Vitro and in Vivo...68
12. Disintegration of Dosage Forms in Vivo...74
13. Correlation of Physiological Availability of Drugs with in Vitro Disintegration Times...82
14. Theory of Tablet Disintegration and Factors Affecting Disintegration Time of Tables and Capsules...89
15. Introduction to Rate of Dissolution in Vitro and in Vivo...98
16. Measurment and Interpretation of in Vitro Rates of Dissolution...104
17. Measurment of in Vitro Rates of Dissolution from Capsules and Tablets...110
18. Factors Affecting Rate of Dissolution and interpretation of Dissolution Rate Data From in Vitro Rate of Dissolution Data...121
19. Theoretical anf Practical Considerations in Correlllation of in Vivo Data With in Vitro Rate of Dissolution Data...121
20. Rank Order Correlation of in Vivo Data With in Vitro Rate of Dissolution Data...125
21. Quantitative Corellations of in Vivo Data in Vitro Rate of Dissolution Data...140
22. Oral Sustained-Release and Prolonged-Action Medication...148
23. Enteric Coatings...158
24. Generic Equivalence and Inequivalence of Oral Products...166
25. Method of Estimation of Biovailability...180
26. Quality Control...190
27. Rectal Absorption...214
28. Theory and Practice ofAdjusting Dosage of Drugs on the Basic of Endogeneus Creatinine Clearence of Serum Creatinine Concentraion...222

Relevant Pharmacokinetics
29. Introduction to Pharmacokinetic...237
30. Some Important Pharmacokinetic Concepts...242
31. The Kidney and Urinary Excreation...247
32. Half-Life and Volume of Distribution...252
33. Body Water Compartments and the Distribution of Drugs...260
34. Types of Data, Derived Parameters and Analyses. Absorption Models...266
35. Introduction to Compartment Models...270
36. Percent Absorbed-Time Plots Based and Absorption...278
37. Percent Absorbed-Time Plots Based on the Two Compartment Open model...285
38. Integrated Equations for Several Pharmacokinetic Models...292
39. Determination of Biovailability or Relative Absortion Efficiency from Plasma Concentrations...297
40. A New Generalized Nonlinear Pharmacokinetic Model and Its Implications...302
41. Mathematical Methods, Part I...318
42. Mathematical Methods, Part II...325
43. Chronological Bibliography of Pharmacokinetics eith Addtional Author Index...331

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Ketersediaan

6157Wagb

615.7/Wag/b

Perpustakaan STIKes BTH (8)

Tersedia

Informasi Detail

Judul Seri

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No. Panggil

615.7/Wag/b

Penerbit

Illinois : Drug Intelligence Publication., 1971

Deskripsi Fisik

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Bahasa

English

ISBN/ISSN

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Klasifikasi

615.7

Tipe Isi

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Tipe Media

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Tipe Pembawa

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Edisi

First Edition

Subjek

Biopharmaceutics and Relevant Pharmacokinetics

Info Detail Spesifik

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Pernyataan Tanggungjawab

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Versi lain/terkait

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